Platelet-Rich Plasma (PRP) Injections to treat knee osteoarthritis

Non-surgical management of knee osteoarthritis (OA)

Regarding intra-articular infiltrative therapy, the use of hyaluronic acid is recommended in cases of chronic knee OA, platelet-rich plasma (PRP) as second line

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Intra-articular injections of cortisone is effective and preferred for severe acute symptoms

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Keywords: knee osteoarthritis, lifestyle changes, physical therapy, pharmacologic treatment, injections, hyaluronic acid, cortisone, opioids, glucosamine, chondroitin, balneotherapy

Analysis: The article is a well-written and comprehensive review of the non-surgical management of knee OA. It provides a clear overview of the available treatment options and makes evidence-based recommendations for their use.  The article also addresses the importance of patient education and self-management in the treatment of knee OA.: lifestyle changes, particularly weight management combined with physical exercise and hydrotherapy.  It recommends using cortisone injection for acute symptoms and considering hyaluronic acid or prp for chronic symptoms. However, it acknowledges that the evidence base for some treatments, such as PRP is still limited

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